Menjarou (Weight Loss Pen)
Questions about “obesity” and “weight loss” are among the most common concerns I encounter in the clinic. Nowadays, obesity is no longer just about body shape or appearance it is a serious health issue that clearly has long-term effects on the body.
In addition to lifestyle modification such as diet control and regular exercise, medical weight loss options have continued to evolve. One of the newer approaches is the use of a weight loss pen, a prescription injectable medication designed to help regulate appetite and improve metabolic control. These medications work by influencing hormones involved in hunger and satiety, helping patients feel full longer and reduce overall calorie intake.
This treatment is considered a medical therapy and is not suitable for everyone. A comprehensive medical evaluation is necessary to assess overall health, review potential risks, and determine whether this option is appropriate for each individual.
🩺 Obesity… is not as minor as it may seem.
Overweight and obesity can increase the risk of developing various diseases in the future, including:
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Diabetes mellitus
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Hyperlipidemia
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Hypertension
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Coronary artery disease
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As well as an increased risk of certain types of cancer
Many individuals attempt to lose weight through dietary control, regular exercise, and lifestyle modification, which are considered the most fundamental and effective approaches. However, it is understandable that in reality, some people have limited time, work-related fatigue, or underlying medical conditions that make consistent self-care difficult to maintain.
Are traditional weight loss medications truly effective?
In the past, many individuals chose oral weight loss medications. Although these medications could lead to rapid weight reduction, they were often associated with side effects such as:
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Palpitations and rapid heartbeat
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Insomnia and restlessness
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Hallucinations
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Risk of dependence
Additionally, once the medication was discontinued, weight regain was common.
For these reasons, newer alternatives have been developed that offer improved safety profiles and are supported by clinical research — including subcutaneous weight control injection pens.
🔹 What is a Weight Loss Pen?
A weight loss pen is an injectable medication device containing drugs in the GLP-1 receptor agonist group, such as:
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Liraglutide
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Semaglutide
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Tirzepatide
These medications mimic natural hormones in the body and help to:
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Promote earlier satiety
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Prolong the feeling of fullness
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Reduce appetite
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Slow gastric emptying
As a result, patients are better able to control food intake and achieve meaningful weight reduction. However, treatment must be combined with proper dietary control and regular exercise, and should always be undertaken under medical supervision.
Primary Mechanisms of Action
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Reduces appetite by signaling the brain to decrease food intake
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Slows stomach emptying, leading to prolonged fullness and reduced snacking
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Helps regulate blood glucose levels, which is particularly beneficial for patients with diabetes
Common Medications Used in Weight Loss Pens
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Liraglutide – administered once daily (e.g., Saxenda)
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Semaglutide – administered once weekly (e.g., Wegovy, Ozempic)
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Tirzepatide – administered once weekly (e.g., Mounjaro)
🔹Getting to Know Menjarou (Mounjaro-Tirzepatide)
Mounjaro, with the generic name Tirzepatide, is a newer injectable medication developed by Eli Lilly & Co., United States. It has been approved by the U.S. FDA for the treatment of type 2 diabetes and is also used for weight management. It is currently available in several countries, including Thailand.
A key feature of Mounjaro is that it is classified as a dual agonist, meaning it mimics the action of two hormones simultaneously:
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GLP-1: Helps reduce appetite, promotes earlier satiety, and prolongs the feeling of fullness.
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GIP: Supports fat metabolism and appropriately stimulates insulin secretion.
Therefore, Mounjaro may be described as addressing both
“appetite control + metabolic enhancement” simultaneously.
Weight Loss Outcomes from Clinical Studies
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In the first month, average weight reduction of approximately 3–5 kilograms (starting dose of 2.5 mg once weekly).
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Within 18 months, body weight may decrease by approximately 15–22% of initial body weight.
Note: Results vary depending on the individual, dietary control, physical activity, and the body’s response to treatment.
Who Is Menjarou Suitable For?
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Individuals with a BMI ≥ 30 (obesity)
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Individuals with a BMI ≥ 27 accompanied by comorbidities such as diabetes, hypertension, or hyperlipidemia
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Individuals who have not achieved satisfactory results with conventional weight loss methods
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Individuals with prediabetes
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Individuals seeking safe and medically supervised appetite control
Precautions and Contraindications
Not recommended for individuals who:
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Have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN 2)
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Are pregnant, breastfeeding, or planning to conceive
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Have a history of pancreatitis
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Have severe renal impairment
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Are under 12 years of age
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Have a known hypersensitivity to Tirzepatide
🩺 Self-Care Before and After Injection
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Consult a physician and undergo a medical evaluation before initiating treatment.
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Administer the injection once weekly on a consistent schedule.
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Consume smaller meals and avoid high-fat or fried foods.
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Maintain adequate hydration.
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Engage in light to moderate exercise regularly.
Common side effects during the initial period may include nausea, abdominal discomfort, and constipation. These symptoms typically improve within 2–4 weeks. If severe symptoms occur, immediate medical attention is advised.
🩺 Doctor’s Summary
A weight loss pen is not a miracle cure, but it can be an effective and safe supportive tool when used appropriately under medical supervision.
Sustainable weight reduction is about long-term health management — not simply the number on the scale.
If you would like further consultation, you are welcome to schedule an appointment for an individualized medical assessment.